Spotlight on L-Theanine

On our journey to provide anxiety support to pets, TrueCalm™ was carefully formulated to include only the very best ingredients - including L-Theanine. L-Theanine has an amazing history of anti-stress effects and we are proud to include this in our hemp-based TrueCalm™ chews for dogs.

TrueCalm™ is a great way to give your dog support in stressful situations including experiencing loud or busy environments, trips to the vet - and even when dogs are privy to experiencing their owner's stressful times.  Check out a little bit of the science behind it, and consider TrueCalm
™ for your pet!


​L-Theanine Reduces Psychological and Physiological Stress Responses.

Kimura K1Ozeki MJuneja LROhira H.

L-Theanine is an amino acid contained in green tea leaves which is known to block the binding of L-glutamic acid to glutamate receptors in the brain. Because the characteristics of L-Theanine suggest that it may influence psychological and physiological states under stress, the present study examined these possible effects in a laboratory setting using a mental task as an acute stressor. 

Twelve participants underwent four separate trials: one in which they took L-Theanine at the start of an experimental procedure, one in which they took L-Theanine midway, and two control trials in which they either took a placebo or nothing. The experimental sessions were performed by double-blind, and the order of them was counterbalanced.

The results showed that L-Theanine intake resulted in a reduction in the heart rate (HR) and salivary immunoglobulin A (s-IgA) responses to an acute stress task relative to the placebo control condition. Moreover, analyses of heart rate variability indicated that the reductions in HR and s-IgA were likely attributable to an attenuation of sympathetic nervous activation.

Thus, it was suggested that the oral intake of L-Theanine could cause anti-stress effects via the inhibition of cortical neuron excitation.

(Source: ​
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